Molecular guide system peptides and uses thereof
AssigneeSRI International
InventorsKathlynn C. Brown, Nathan Collins, Shunzi “Susan” Li, Curtis Allred, Keen Chung, Michael McGuire
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Abstract
Disclosed are compositions comprising an antibody conjugated to one or more molecular guidance system (MGS) peptides. Disclosed are methods of treating a subject in need thereof comprising administering to the subject in need thereof an effective amount of an antibody conjugated to one or more MGS peptides, wherein the antibody targets an intracellular target involved in the disease process. Disclosed are methods of targeting an intracellular target comprising administering an antibody conjugated to one or more MGS peptides, wherein the antibody targets an intracellular target.
Claims13
A composition comprising an antibody conjugated to one or more molecular guidance system (MGS) peptides, directly or via a linker, wherein the one or more MGS peptides are selected from the group consisting of SEQ ID NOs:
- 2, 3, 20-22, and 38-41.
A molecular guidance system (MGS) peptide selected from the group consisting of SEQ ID NOs:
- 2, 3, 20-22, and 38-41.
Dependencies are inferred from the claim text.