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US 11,964,008 B2Granted
Method for inactivating zika virus and for determining the completeness of inactivation
AssigneeTakeda Vaccines, Inc.
InventorsJill A. Livengood, Holli Giebler, Hansi Dean, Tatsuki Satou, Raman Rao, Jackie Marks, Mark Lyons, Asae Shintani, James Gifford, Sushma Kommareddy
Life of this patent
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Abstract
The present disclosure relates to methods for inactivating a Zika virus which can be used in vaccines and immunogenic compositions. The present disclosure also relates to a method for determining the completeness of inactivation of an arbovirus preparation.
Claims30
A pharmaceutical composition comprising an inactivated Zika virus preparation, wherein the inactivated Zika virus preparation comprises less than 1.0 TCID50 of residual replicating virus.
Dependencies are inferred from the claim text.