Preliminary diagnoses of cut tissue sections
AssigneeClarapath, Inc.
InventorsPartha P. Mitra, Charles R. Cantor, Baris Yagci, Steven Smith
Life of this patent
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Abstract
A system for optical interrogation of tissue samples, the system including: a microtome configured to section one or more tissue sections from a tissue block, the one or more tissue sections including one or more tissue samples; a transfer medium configured to gather the one or more tissue sections and to transfer the one or more tissue sections to one or more slides; and an optical interrogation system including an illumination system configured to illuminate the one or more tissue sections and an imaging system configured to perform an imaging analysis on the one or more tissue sections illuminated with the illumination system.
Claims18
A system for optical interrogation of tissue samples, the system comprising:
- a microtome configured to section one or more tissue sections from a tissue block, the one or more tissue sections comprising one or more tissue samples;
- a transfer medium configured to gather the one or more tissue sections and to transfer the one or more tissue sections to one or more slides;
- and
- an optical interrogation system comprising an illumination system configured to illuminate the one or more tissue sections and an imaging system configured to perform an imaging analysis on the one or more tissue sections illuminated with the illumination system, wherein the optical interrogation system is mounted on a moveable stage such that the imaging analysis of the one or more tissue sections is performed at the microtome, on the transfer medium, or on the one or more slides.
A system for optical interrogation of tissue samples, the system comprising:
- a microtome configured to section one or more tissue sections from a tissue block for transfer to one or more slides by a transfer medium, the one or more tissue sections comprising one or more tissue samples;
- an optical interrogation system comprising an illumination system configured to illuminate the one or more tissue sections and an imaging system configured to perform an imaging analysis of the one or more tissue sections illuminated with the illumination system, wherein the optical interrogation system is mounted on a moveable stage such that the imaging analysis of the one or more tissue sections is performed at the microtome, on the transfer medium, or on the one or more slides;
- and
- a processor in communication with the optical interrogation system, the processor being programmed to receive imaging data indicative of the imaging analysis from the optical interrogation system and to present the imaging data for an analysis of the one or more tissue sections to determine a presence or an absence of one or more abnormalities.
A system for optical interrogation of tissue samples, the system comprising:
- a microtome configured to section one or more tissue sections from a tissue block, the one or more tissue sections comprising one or more tissue samples;
- a transfer medium configured to gather the one or more tissue sections and to transfer the one or more tissue sections to one or more slides;
- an optical interrogation system comprising an illumination system configured to illuminate the one or more tissue sections and an imaging system configured to perform an imaging analysis on the one or more tissue sections illuminated with the illumination system, wherein the optical interrogation system is mounted on a moveable stage such that the imaging analysis of the one or more tissue sections is performed at the microtome, on the transfer medium, or on the one or more slides;
- and
- a processor being programmed to receive imaging data indicative of the imaging analysis from the optical interrogation system, to perform an analysis of the one or more tissue samples for one or more biomarkers indicative of a disease, and to cause the microtome to section additional one or more tissue sections if the one or more biomarkers are detected.
Dependencies are inferred from the claim text.