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US 11,959,144 B2Granted
Prostate cancer detection kit or device, and detection method
AssigneesToray Industries, Inc., National Cancer Center
InventorsSatoshi Kondou, Hitoshi Nobumasa, Satoko Kozono, Hiroko Sudo, Junpei Kawauchi, Takahiro Ochiya, Nobuyoshi Kosaka
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Abstract
An object of the present invention is to provide a kit or a device for the detection of prostate cancer and a method for detecting prostate cancer. The present invention provides a kit or a device for the detection of prostate cancer, comprising a nucleic acid capable of specifically binding to a miRNA in a sample of a subject, and a method for detecting prostate cancer, comprising measuring the miRNA in vitro.
Claims6
A method for detecting prostate cancer in a human subject, comprising:
- measuring an expression level of hsa-miR-6741-5p in a blood, serum, or plasma sample from the subject;
- comparing the measured expression level of hsa-miR-6741-5p to a control expression level in a sample from a healthy subject;
- detecting a decreased level of hsa-miR-6741-5p in the sample from the subject as compared to the control expression level from the sample from the healthy subject;
- wherein the decreased level of hsa-miR-6741-5p indicates that the subject has prostate cancer;
- and
- wherein the method further comprises treating the subject for the prostate cancer or performing a diagnostic procedure on the subject with the prostate cancer;
- wherein the treating comprises surgery, radiotherapy, chemotherapy or the combination thereof, and
- wherein the diagnostic procedure comprises rectal examination, transrectal ultrasonography of the prostate, or imaging of prostate tissue.
5 more elements
Dependencies are inferred from the claim text.