Optimization of fermentation processes

A system for adjusting and/or optimize a fermentation process performed in at least one U-loop fermenter, the system comprising:

• at least one U-loop fermenter being operatively connected to a computer
• the computer comprising a processor and being operatively connected to a database;
• at least one analysis apparatus for repetitively providing a test value of at least one parameter of one U-loop fermenter;
• a data interface for repetitively entering the test value of the at least one parameter in the database,
• the database comprising at least one control value,
• wherein the database is adapted to store multiple database entries representing the test value of the at least one parameter at various points in time and adapted to store multiple database entries representing the at least one control value at various points in time, wherein the processor is programmed to:
• perform at least one mathematical analysis of the test value providing a calculated test value, and/or the at least one control value providing at least one calculated control value;
• selecting, on the basis of the calculated test value and/or on the at least one calculated control value, an adjustment to be introduced into at least one other U-loop fermenter to benefit from a change made in the at least one U-loop fermenter;
• wherein the at least one mathematic analysis comprises that one or more substrates or metabolites are modelled, wherein the one or more substrates or metabolite inhibit growth of a microorganism in the at least one U-loop fermenter, and wherein the one or more substrates or metabolites, which are modelled in the mathematical analysis is or are selected from the group consisting of nitrite, nitrate, ammonium, an acid or a derivative hereof;
• and
• wherein the at least one mathematical analysis comprises a modelling of a conceptually partitioned U-loop fermenter into sections or parts.