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US 11,958,897 B2Granted
Anti-VAMP2 antibody for inhibiting snare complex and use thereof
AssigneeHauul Bio
InventorsHee-Jun Na, Yun-Suk Lee, Je-Ok Yoo, Kwang-Soon Lee, Kang Seung Lee, Seung Je Min
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Abstract
The present invention relates to an anti-VAMP2 antibody that inhibits SNARE complex and uses thereof, and more specifically, the present invention relates to an anti-VAMP2 antibody or antigen-binding fragments thereof comprising heavy and light chain CDRs of a specific sequence. The anti-VAMP2 antibody is expected to be useful for improving or treating skin wrinkles by inhibiting SNARE complex formation.
Claims4
An anti-VAMP2 antibody or antigen-binding fragment thereof comprising:
- a light chain variable region comprising a light chain CDR1 comprising the amino acid sequence of SEQ ID NO:
- 1, a light chain CDR2 comprising the amino acid sequence of SEQ ID NO:
- 2 and a light chain CDR3 comprising the amino acid sequence of SEQ ID NO:
- 3;
- and
- a heavy chain variable region comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO:
- 4, a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO:
- 5, and a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO:
- 6.
6 more elements
Dependencies are inferred from the claim text.