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US 11,958,857 B1Granted
5-(1H-indol-3-yl)-1,3-substitutedpyrimido[4,5-d]pyrimidine-2,4,7(1H,3H,8H)-trione as anticancer agents
AssigneeKing Faisal University
InventorsKatharigatta N. Venugopala, Rashmi Venugopala, Vinuta Kamat, Amit Kumar
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Abstract
Methods of treating cancer in a patient by administering 5-(1H-indol-3-yl)-1,3-substituted pyrimido[4,5-d]pyrimidine-2,4,7(1H,3H,8H)-trione to a patient in need thereof.
Claims13
A compound having the formula I:
- or a pharmaceutically acceptable salt, ester, stereoisomer, or solvate thereof, wherein:
- R1 is selected from the group consisting of hydrogen and methyl;
- R2 is selected from the group consisting of hydrogen and methyl;
- and
- Y is selected from the group consisting of O and S.
2 more elements
A compound having the formula I:
- or a pharmaceutically acceptable salt, ester, stereoisomer, or solvate thereof, wherein:
- R1 and R2 are both hydrogen or are both methyl;
- and
- Y is selected from the group consisting of O and S.
1 more element
Dependencies are inferred from the claim text.