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US 11,958,855 B2Granted
Aurora kinase inhibitors for inhibiting mitotic progression
AssigneeMillennium Pharmaceuticals, Inc.
InventorsChristopher F. Claiborne, Todd B. Sells, Stephen G. Stroud
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Abstract
The present invention relates to compounds and methods for the treatment of cancer. In particular, the invention provides potent inhibitors of Aurora A kinase, pharmaceutical compositions comprising the compounds, and methods of using the compounds for the treatment of cancer.
Claims10
A method for treating lung cancer in a patient having the lung cancer, comprising administering to the patient a therapeutically effective amount of a compound of formula:
- or a pharmaceutically acceptable salt thereof in combination with a therapeutic agent selected from the group consisting of cytotoxic agents, radiotherapeutic agent, and immunotherapeutic agent, and wherein the therapeutic agent is administered as a separate dosage form.
Dependencies are inferred from the claim text.