Solid forms comprising an oxime ether compound, compositions and methods of use thereof
AssigneeNovartis AG
InventorsLianfeng Huang, Daozhong Zou
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Abstract
Provided herein are formulations, processes, solid forms and methods of use relating to (E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid.
Claims38
A crystalline solid form comprising an HBr salt of (E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid (Compound 1) or a tautomer thereof.
A crystalline solid form comprising a maleate salt of (E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid (Compound 1), or tautomer thereof.
A crystalline solid form comprising a malonate salt of (E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid (Compound 1), or a tautomer thereof.
A crystalline solid form comprising an edisylate salt of (E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid (Compound 1), or a tautomer thereof.
A crystalline solid form comprising a tosylate salt of (E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid (Compound 1), or a tautomer thereof.
Dependencies are inferred from the claim text.