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US 11,958,018 B2Granted
Tangential flow filtration systems and methods
AssigneeRepligen Corporation
InventorsMichael Bransby, Derek Carroll, Philip Yuen, Ralf Kuriyel
Life of this patent
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Abstract
The disclosure provides tangential flow depth filtration (TFDF) systems which exhibit improved filter fluxes and process capacities and reduced fouling characteristics. The TFDF systems of the disclosure optionally utilize tubular depth filters (TDF). Methods are provided which include the passage of a non-laminar flow through at least a portion of a length of a TDF in a TFDF system.
Claims19
A method of filtering a fluid, comprising:
- passing the fluid through a filter having first and second ends and comprising at least one tubular depth filter unit (TDF) extending between and open to each of the first and second ends of the filter, the at least one TDF comprising an inner diameter of at least 1 mm and comprising a porous wall having a thickness of at least 100 μm;
- wherein passing the fluid comprises the fluid flowing in a non-laminar manner through the at least one TDF.
Dependencies are inferred from the claim text.