Sensor-based pain management systems and methods

A system comprising:

• a sensor circuit coupled to a plurality of physiological sensors each having respective sensitivities to physical activity, the plurality of physiological sensors configured to sense respective physiological signals from a patient;
• and
• a controller circuit configured to:
• receive information about a physical activity level in the patient;
• select, from the plurality of physiological sensors, at least one physiological sensor based on the received physical activity level, including to select a first physiological sensor to sense a first physiological signal under a first sensor operating mode when the received physical activity level is above a threshold, and to select a second physiological sensor different from the first physiological sensor to sense a second physiological signal under a second sensor operating mode when the received physical activity level is below the threshold;
• and
• generate a control signal to initiate or adjust a neuromodulation therapy to the patient based on the physiological signal sensed by the selected at least one physiological sensor.

A method of operating a neuromodulation device to provide neuromodulation to a patient, the method comprising:

• determining a baseline physical activity pattern at a baseline state of the patient;
• detecting a physical activity pattern from a motion signal sensed from the patient, the physical activity pattern representing a change in physical activity over time;
• via a physiological sensor, initiating sampling of a physiological signal based on a dissimilarity between the detected physical activity pattern and the baseline physical activity pattern;
• and
• via a control circuit, initiating or adjusting a neuromodulation therapy in response to the sampled physiological signal satisfying a condition.