Apparatus for performing peritoneal dialysis

An apparatus for performing peritoneal dialysis, comprising means for delivering dialysis fluid to the peritoneal cavity of a patient and draining dialysis fluid from the peritoneal cavity, a measurement device means for continuously or discontinuously measuring the fluid pressure of the delivered fluid and for measuring an intraperitoneal pressure of the patient, and a control unit operably connected to said means and the measurement device means, characterized in that

• the control unit is configured to establish a relationship of the measured intraperitoneal pressure to intraperitoneal volume and to analyse this relationship to obtain an average hydraulic conductance (LpS) of a peritoneal membrane of the patient by the steps of
• determining a first rate of change of intraperitoneal volume (Jv_net(t1)) at a first point in time and a second rate of change of intraperitoneal volume (Jv_net(t2)) at a second point in time,
• determining a first average of the measured intraperitoneal pressure (Pip(t1)) in the peritoneal cavity at the first point in time and a second average of the measured intraperitoneal pressure (Pip(t2)) in the peritoneal cavity at the second point in time,
• determining a first glucose concentration (Cg(t1)) of the dialysis fluid in the peritoneal cavity at the first point in time and a second glucose concentration (Cg(t2)) of the dialysis fluid in the peritoneal cavity at the second point in time, and
• determining the average hydraulic conductance (Lp), and
• the control unit is further configured to (i) adapt at least one treatment parameter in a peritoneal dialysis treatment based on the determining steps, wherein the at least one treatment parameter comprises at least one of a filling volume for dialysis fluid in the peritoneal cavity, a dwell time, or an optimum number of inflow-outflow cycles, and
• (ii) perform the peritoneal dialysis treatment with the apparatus, adapting the at least one treatment parameter, comprising controlling the means for delivering and draining.