Wnt compositions and methods for purification
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsJill Helms, Girija Dhamdhere
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Abstract
Disclosed herein are methods, processes, compositions, and kits for generating bone graft materials for use at a site of bone defect that utilizes a composition which contains liposomal Wnt polypeptide, such as liposomal Wnt3a polypeptide, liposomal Wnt5a polypeptide, or liposomal Wnt10b polypeptide. Also disclosed herein are methods, processes, compositions, and kits for enhancing mammalian bone marrow cells that utilizes a composition which contains liposomal Wnt polypeptide, such as liposomal Wnt3a polypeptide, liposomal Wnt5a polypeptide, or liposomal Wnt10b polypeptide.
Claims20
A composition comprising:
- a functionally active mammalian Wnt polypeptide;
- and
- an aqueous solution comprising liposomes, wherein the liposomes comprise a sterol lipid, and wherein the liposomes have a net charge of 0 at a pH of between about 6.5 and about 8.0.
Dependencies are inferred from the claim text.