Long lasting effect of new botulinum toxin formulations

A method for treating a condition in a patient in need thereof, the method comprising the step of locally administering a therapeutically effective amount of an animal-protein-free botulinum toxin composition, wherein the composition is administered at an interval of time between a first treatment and a second treatment effective to maintain alleviation of at least one symptom of the condition, that is greater than the interval of time for an animal-protein-containing botulinum toxin composition dosed at the same amount and administered in the same manner and to the same location(s) as that of the animal-protein-free composition, and wherein the condition is facial line.

A method to reduce frequency of treatment with botulinum toxin for a condition in a patient thereby affected, comprising:

• providing an animal-protein free botulinum toxin composition for local administration by injection at a treatment site, wherein administration of a first therapeutically effective amount is separated by a time interval from administration of a second therapeutically effective amount, said time interval being greater than a time interval between first and second treatment of a therapeutically effective amount of an animal-protein containing botulinum toxin composition administered by injection at the treatment site, and wherein the condition is facial line.