Liquid dosage forms of Imatinib
AssigneeShorla Pharma Ltd.
InventorsSandip Mehta, Vijay Patel, Manish Umrethia, Jayanta Kumar Mandal
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Abstract
Imatinib is approved and marketed in solid oral dosage forms which may be dispersed in water or apple juice for patients having swallowing difficulty. Dispersion of Imatinib solid dosage forms in apple juice may increase palatability and patient compliance but apple juice may not be available all the time for administration. Further, dispersion of Imatinib solid oral dosage forms may not administer correct and consistent dose of medicine every time. The present invention therefore provides liquid dosage forms of Imatinib which correctly and consistently administers correct dose of drug to the patients.
Claims1
A liquid dosage form consisting of:
- about 0.01% to about 25% w/v of imatinib mesylate;
- about 25% to about 60% w/v of glycerin;
- about 0.01% to about 10% w/v of sodium benzoate;
- about 0.01% to about 10% w/v of liquid maltitol;
- citric acid;
- acesulfame potassium;
- strawberry flavor;
- and
- water.
Dependencies are inferred from the claim text.