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US 11,957,680 B2Granted
Pyruvate kinase activators for use in treating blood disorders
AssigneeAgios Pharmaceuticals, Inc.
InventorsGiovanni Cianchetta, Tao Liu, Anil Kumar Padyana, Zhihua Sui, Zhenwei Cai, Dawei Cui, Jingjing Ji
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Abstract
Described herein are compounds that activate pyruvate kinase R, pharmaceutical compositions and methods of use thereof. These compounds are represented by Formula (I): wherein R1, R2, L1, and L2 are as defined herein.
Claims14
A compound having a structural formula selected from:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.