JAK1 pathway inhibitors for the treatment of vitiligo
AssigneeIncyte Corporation
InventorsPaul Smith, Kurt Andrew Brown, Michael D. Howell, Fiona Kuo, James Lee, Leandro Luiz Dos Santos, Beth Rumberger
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Abstract
This disclosure relates to JAK1 pathway inhibitors and their use in treating vitiligo.
Claims13
A method for treating non-segmental vitiligo in a subject, said method comprising administering to the subject a therapeutically effective amount of JAK1 pathway inhibitor 4-[3-(cyanomethyl)-3-(3′,5′-dimethyl-1H,1′H-4,4′-bipyrazol-1-yl)azetidin-1-yl]-2,5-difluoro-N-[(1S)-2,2,2-trifluoro-1-methylethyl]benzamide, or a pharmaceutically acceptable salt thereof, wherein the JAK1 pathway inhibitor, or pharmaceutically acceptable salt thereof is administered in a daily dose of about 10 mg to about 80 mg on a free base basis.
Dependencies are inferred from the claim text.