Compositions comprising citrulline and leucine and their use in the treatment of diabetes and metabolic syndrome
AssigneeSociete des Produits Nestle S.A.
InventorsChristophe Moinard, Gabrielle Ventura, Denis Breuille, Christian Darimont-Nicolau, Luc Cynober
Life of this patent
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Abstract
Compositions contain citrulline and leucine or a metabolite thereof, such as hydroxyisocaproic acid (HICA) or beta-hydroxy-beta-methylbutyrate (HMB), including, for example, a synergistic amount of citrulline and leucine. Such compositions may be used in methods for treatment of pre-diabetes, metabolic syndrome, or diabetes.
Claims12
A method of treating a condition selected from the group consisting of pre-diabetes, diabetes, and metabolic syndrome in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of citrulline and a therapeutically effective amount of leucine or a metabolite thereof.
Dependencies are inferred from the claim text.