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US 11,953,472 B2Granted
System and method for component interconnection in HPLC
AssigneeDionex Softron GmbH
InventorsThomas Wachinger, Christoph Hollnagel
Life of this patent
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Abstract
A system for component interconnection for use in liquid chromatography includes a first switching valve and a second switching valve. A first connecting line fluidly connects the first switching valve to the second switching valve. A second connecting line fluidly connects the first switching valve to the second switching valve. A metering device is located in the first connecting line.
Claims18
A system for component interconnection for use in Liquid Chromatography comprising:
- a. a first switching valve;
- b. a second switching valve;
- c. a first connecting line fluidly connecting the first switching valve to the second switching valve;
- d. a second connecting line fluidly connecting the first switching valve to the second switching valve;
- e. a metering device located in the first connecting line;
- wherein the system further comprises:
- an analytical pump adapted to generate an analytical flow in the system, a separation column and a trap column fluidly connected to two ports of the first switching valve, wherein the system further comprises a sample pick up means adapted to retrieve a sample and a seat adapted to receive the sample pick up means;
- wherein the first connecting line comprises:
- one end fluidly connected to the second switching valve, tubing connecting the second switching valve to the metering device and tubing connecting the metering device to the sample pick up means.
6 more elements
A method for sample loading comprising the steps of:
- a. providing a liquid chromatography system comprising:
- a first switching valve, a second switching valve, a first connecting line fluidly connecting the first switching valve to the second switching valve, a second connecting line fluidly connecting the first switching valve to the second switching valve, a metering device located in the first connecting line, a separation column, a trap column, and an analytical pump;
- wherein the system further comprises:
- a sample pick up means adapted to retrieve a sample and a seat adapted to receive the sample pick up means;
- wherein the first connecting line comprises:
- one end fluidly connected to the second switching valve, tubing connecting the second switching valve to the metering device and tubing connecting the metering device to the sample pick up means;
- and b. loading a sample into the trap column;
- and c. fluidly connecting the trap column to the separation column and the analytical pump to the trap column via the first switching valve and generating a flow from the analytical pump to the separation column.
5 more elements
Dependencies are inferred from the claim text.