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AssigneesMedizinische Hochschule Hannover, Twincore Zentrum FüR Experimentelle Und Klinische Infektionsforschung GmbH, Technische UniversitäT Dresden
InventorsDaniel Todt, Sibylle Haid, Martin Wetzke, Gesine Hansen, Chris Lauber, Lars Kaderali, Thomas Pietschmann
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The present invention pertains to a method for the identification of genetic variants that are associated with the severity of an infectious disease. The invention further pertains to a set of genetic factors associated with the severity of Human respiratory syncytial virus (HRSV) infection, for example in human infants. The genetic polymorphisms identified according to the present invention are for use in the diagnostic of infectious diseases and patient stratification in order to avoid or reduce the occurrence of fatal events during infection or to elect the most appropriate therapeutic approach to treat the disease.
A method for treatment of a HRSV infection in a subject in need of the treatment, comprising administering to the subject an agonist of transmembrane protein 259 (TMEM259);
Dependencies are inferred from the claim text.