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US 11,952,461 B2Granted
Siloxy polyethylene glycol and derivatives thereof
AssigneeSunBio Inc.
InventorsKwang Nho, Minjung Ahn, Changmin Hyun, Junghoon Lee
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Abstract
Disclosed are a novel monofunctional polyethylene glycol (PEG) and derivatives thereof. More particularly, one terminal of each of the monofunctional polyethylene glycol and derivatives thereof is modified with a siloxy group. The novel monofunctional polyethylene glycol (PEG) offers an alternative to methoxy polyethylene glycol.
Claims10
A trialkyl siloxy polyethylene glycol (PEG) represented by Formula 1 below and derivatives thereof:
- wherein a, b, and c are independently an integer of 0 to 10,
- n is an integer of 2 to 10,000,
- x is an integer of 0 to 5,
- y is an integer of 0 or 1, and
- R is selected from the group consisting of hydrogen, an amine group, a thiol group, a substituted or unsubstituted aryl group, a, and C2-C20 heterocyclic group.
2 more elements
Dependencies are inferred from the claim text.