Benzodiazepine derivatives as RSV inhibitors
AssigneeEnanta Pharmaceuticals, Inc.
InventorsBrian C. Shook, In Jong Kim, Thomas P. Blaisdell, Jianming Yu, Joseph D. Panarese, Yat Sun Or
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Abstract
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV). The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from RSV infection. The invention also relates to methods of treating an RSV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
Claims9
A compound represented by the formula
- or a pharmaceutically acceptable salt thereof, wherein
- R4 is
- and R4 is substituted with at least one substituent selected from the group consisting of CH3, CN, fluoro, chloro, CH3O—, CH3C(O)—, CH3OCH2—, CH3OCH2CH2O—, —CF3, CF3O—
Dependencies are inferred from the claim text.