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US 11,952,361 B1Granted
2-(1-(3-(dimethylamino)propyl)-4,5-diphenyl-1H-imidazol-2-yl) pyridin-3-ol as an antitumor and antimicrobial compound
AssigneeKing Faisal University
InventorsHany Mohamed Abd El-Lateef Ahmed, Mai Mostafa Khalaf Ali, Antar Ahmed Abdelhamid Ahmed, Adel A. Marzouk, Fawy M. Abd El Latif
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Abstract
A compound 2-(1-(3-(dimethylamino)propyl)-4,5-diphenyl-1H-imidazol-2-yl)pyridin-3-ol compound, its synthesis, and its use as an anticancer, anti-inflammatory, and/or antimicrobial agent.
Claims7
A method of making 2-(1-(3-(dimethylamino)propyl)-4,5-diphenyl-1H-imidazol-2-yl)pyridin-3-ol, the method comprising:
- adding benzil, 6-hydroxypyridine-2-carbaldehyde, ammonium acetate, and N,N-dimethyl-3-aminopropane to piperidinium hydrogen sulfate in an oil bath to obtain a reaction mixture;
- heating the reaction mixture with stirring until reaction completion to obtain a crude product;
- purifying the crude product by recrystallization using absolute ethyl alcohol;
- and
- obtaining the 2-(1-(3-(dimethylamino)propyl)-4,5-diphenyl-1H-imidazol-2-yl)pyridin-3-ol compound.
2 more elements
Dependencies are inferred from the claim text.