Bioenergetically active esters for health and disease
AssigneeUniversity of Kansas
InventorsRussell Swerdlow, Laird Forrest, Jordan Hunt, Heather Wilkins, Eli Michaelis
Life of this patent
Estimating the term…
Abstract
Compounds, compositions, and methods related to bioenergetic metabolism are provided. The compounds and compositions are suited to promote bioenergetic processes including cellular respiration and glycolytic flux and may be used to treat mitochondrial disorders, neurodegenerative diseases (such as Alzheimer's disease (AD), Parkinson's disease, and/or amyotrophic lateral sclerosis), multiple sclerosis, and/or epilepsy.
Claims14
A pharmaceutical composition comprising
- a compound of Formula I
- or a pharmaceutically acceptable salt and/or solvate thereof, wherein both R1 and R2 are
- and
- a pharmaceutically acceptable carrier.
A pharmaceutical composition comprising
- an effective amount of a compound of Formula I
- or a pharmaceutically acceptable salt and/or solvate thereof, wherein both R1 and R2 are
- and
- a pharmaceutically acceptable carrier.
A method for increasing cellular respiration in a cell, the method comprising contacting the cell with a compound of Formula I
- or a pharmaceutically acceptable salt and/or solvate thereof, wherein both R1 and R2 are
Dependencies are inferred from the claim text.