US 11,951,335 B2Granted

Internal organ, injury and pain, pulmonary condition and adipose tissue treatment

AssigneeB.R.H. Medical Ltd.

InventorIlan Feferberg

Life of this patent

Estimating the term…

Loading patent…

Abstract

Ultrasound (US) apparatus and method for applying low energy US onto an internal tissue/organ, including a non-invasive US appliance used on a treatment region over the internal tissue/organ, and an electrical stimulation apparatus for simultaneously inducing interferential electrical stimulation. A controller controls parameters of the electrical stimulation apparatus and the US appliance, and dynamically changes at least one of the parameters, for maintaining the impedance of the body tissue in the treatment region within an impedance range. The US apparatus includes an impedance monitoring apparatus for continuously measuring, tracking, and monitoring impedance in the treatment region, wherein the controller dynamically changes at least one of the parameter in response to the impedance as monitored, for maintaining the impedance within the predefined range. The internal tissue/organ can be a female fertility organ which can be an ovarian follicle, a blood vessel of the uterus (womb), the ovary, the endometrial lining, and the Fallopian tube; a lung, a pulmonary organ, an adipose tissue, ulcer, closed wound, internal injury, inflammation. and nerves.

Claims18

Dependent claims

Ultrasound (US) apparatus for applying low energy US onto an internal tissue/organ, comprising:

(a) a non-invasive external US appliance operational configured to apply low energy US energy, at an US frequency and an US intensity, onto a treatment region over the internal tissue/organ;
(b) an electrical stimulation apparatus comprising two pairs of electrodes configured to induce interferential electrical stimulation configured for positioning at crossed configuration onto the skin at the treatment region in proximity to the internal tissue/organ, by applying, simultaneously with said applying US energy, a first current at a first electric frequency and a first electric intensity via one of said two pairs of electrodes, and a second current at a second electric frequency and a second electric intensity via another of said pairs of electrodes, thereby defining an interference pattern of resonant waves that revolve at an interferential frequency in said treatment region;
(c) an impedance monitoring apparatus configured to continuously track and monitor the impedance of a body tissue in said treatment region;
(d) a controller configured to control parameters of said electrical stimulation apparatus and said US appliance, the controller configured to dynamically change at least one of said parameters in response to the impedance monitored by said monitoring apparatus, for maintaining said impedance within a predefined impedance range, wherein said parameters are selected from the group of electrical stimulation parameters and ultrasound parameters consisting of:
(i) said interferential frequency;
(ii) said interference pattern;
(iii) said US frequency;
and (iv) said US intensity;
and
wherein said internal tissue/organ comprises at least one of:
lung;
pulmonary tissue;
and adipose tissue.

10 more elements

Method for applying low energy ultrasound (US) energy from a non-invasive external US source to an internal body tissue/organ, the method comprising the procedures of:

(a) determining a treatment region over the internal tissue/organ;
(b) positioning onto the skin at the treatment region in proximity to the internal tissue/organ, two pairs of electrodes at crossed configuration of an electrical stimulation apparatus operational for inducing interferential electrical stimulation;
(c) applying interferential electrical stimulation through the electrodes to the treatment region, by applying a first current at a first electric frequency and a first electric intensity via one of said two pairs of electrodes, and a second current at a second electric frequency and a second electric intensity via another of said pairs of electrodes, thereby defining an interference pattern of resonant waves that revolve at an interferential frequency in said treatment region;
(d) transmitting ultrasound (US) waves at an US frequency and an US intensity to the treatment region simultaneously with said applying of interferential electrical stimulation;
(e) continuously monitoring impedance tracked in the treatment region;
and
(f) dynamically changing at least one parameter of said electrical stimulation and said ultrasound, in response to the impedance as monitored, for maintaining the impedance of a body tissue in said treatment region within a predefined impedance range, wherein said parameter comprising one of:
(i) said interferential frequency;
(ii) said interference pattern;
(iii) said US frequency;
and (iv) said US intensity;
and
wherein said internal tissue/organ comprises at least one of:
lung;
pulmonary tissue;
and adipose tissue.

13 more elements

Dependencies are inferred from the claim text.

Facts

Application: 17/060,938Filed 1 Oct 2020 · continuation in part
Priority: IL 2533014 Jul 2017
Published: US 2021/0023398 A128 Jan 2021
Granted: 9 Apr 2024
Term ends: Not estimatedThe source records don’t support an estimate.

Classification20 codes

A61N 7/00
Ultrasound therapy
A61N 1/0476
Structure-related aspects: array electrodes
A61N 1/323
Alternating or intermittent currents: interference currents, i.e. treatment by several currents summed in the body
A61N 1/36031
Control systems: using physiological parameters for adjustment

Family

Application62/657,944Us provisional application · filed 16 Apr 2018
PCT/IL2018/050727Parent of this continuation-in-part · filed 4 Jul 2018
US 2021/0023398 A1Pre-grant publication · published 28 Jan 2021
Application16/628,769Parent of this continuation-in-part
US 11,433,259 B2Parent of this continuation-in-part
US 2020/0139160 A1Published application
US 11,951,335 B2This patent

From the US filing history. Foreign family members aren’t listed.