Drug-coated medical devices
AssigneeMedtronic Vascular, Inc.
InventorsSimone D'Onofrio, Massimo Morero, Bradley Steele, Federica Bellucci, Cassandra Morris
Life of this patent
Estimating the term…
Abstract
A method for coating a medical device includes applying a second layer that includes a second drug on a first layer of on the medical device. The first layer includes a first drug, which may be in crystalline form. By selecting an appropriate solvent use in applying the second layer and appropriate process conditions, the second layer may be applied such that the first drug retains one or more therapeutic properties. For example, the second layer may be applied such that the first drug maintains its crystalline form. The first and second layers may be free of polymer.
Claims17
A method for coating a medical device comprising a first layer comprising a first drug, wherein the first layer is free from polymers and the first drug is an antiproliferative agent, the method comprising:
- applying a solution comprising a second drug and a solvent to form a second layer on the first layer of the medical device, wherein the second drug is an anti-inflammatory agent and the second layer is free from polymers, wherein the first drug in the first layer is in crystalline form and wherein the solution comprising the second drug is applied to the first layer of the medical device such that the first drug maintains its crystalline form.
A medical device comprising
- a body,
- a first layer on the body, wherein the first layer comprises a first drug, wherein the first layer is free from polymers and the first drug is an antiproliferative agent;
- and
- a second layer on the first layer, wherein the second layer comprises a second drug, wherein the second drug is an anti-inflammatory agent and the second layer is free from polymers,
- wherein the first drug in the first layer is in crystalline form.
Dependencies are inferred from the claim text.