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US 11,951,206 B2Granted
Cell housing device
AssigneeVertex Pharmaceuticals Incorporated
InventorsChristopher Thanos, Danya M. Lavin, Briannan E. Bintz, Divya Bhatnagar, John Mills, Megan Billings
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Abstract
The present disclosure provides a cell housing device and a method of manufacturing such a device that has an array of channels to increase the ratio of surface area to volume.
Claims30
A cell housing device, comprising:
- a first membrane having a first surface, and a second surface opposing the first surface;
- a second membrane opposite and attached to the second surface of the first membrane, wherein the first membrane and the second membrane form an enclosed compartment configured to house a cell population, wherein the enclosed compartment includes a plurality of continuous interconnected compartments formed between the first membrane and the second membrane, and wherein at least one of the first membrane and the second membrane is sintered;
- and
- a frame extending at least partially along an outer edge of the first membrane and the second membrane.
1 more element
A cell housing device, comprising:
- a first membrane having a first surface and a second surface opposing the first surface;
- a second membrane opposite and attached to the second surface of the first membrane wherein the first membrane and the second membrane form an enclosed compartment configured to house a cell population, wherein the enclosed compartment includes a plurality of continuous interconnected compartments between the first membrane and the second membrane, and wherein at least one of the first membrane and the second membrane is sintered;
- and
- a frame extending at least partially along an outer edge of the first membrane and the second membrane,
- wherein a thickness of a portion of the device including the first membrane and the second membrane has a thickness between or equal to 50 μm and 500 μm and wherein a length of the device is between or equal to 4.0 cm and 6.0 cm.
2 more elements
Dependencies are inferred from the claim text.