US 11,951,197 B2Granted

Use of volatile compounds to modulate the perception of floral muguet

AssigneeFirmenich SA

InventorsPatrick Pfister, Christie Delaura, Casey Trimmer, Lily Wu, Aleksey Dumer, Florian De Nanteuil

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Abstract

Described herein are compositions and/or ingredients that increase a subject's perception of floral muguet compounds, methods for intensifying a subject's perception of floral muguet compounds, as well as perfumed articles or perfuming compositions including as an active ingredient, at least one compound selected from octanal; (E)-dec-2-enal, 2-phenylpropanal; (E)-but-2-enal; 3-methylbenzaldehyde; 3-(1,3-benzodioxol-5-yl)-2-methylpropanal; (±)-3-(4-methyl-3-penten-1-yl)-3-cyclohexene-1-carbaldehyde, (±)-4-(4-methyl-3-penten-1-yl)-3-cyclohexene-1-carbaldehyde, and mixtures thereof; heptanal, 4-Propan-2-ylbenzaldehyde; (3R)-3,7-dimethyloct-6-enal; (+)-(3S)-3-[(1R)-4-methyl-3-cyclohexen-1-yl]butanal, (+)-(3R)-3-[(1R)-4-methyl-3-cyclohexen-1-yl]butanal, and mixtures thereof; hexanal; 2,6-dimethylhept-5-enal; benzaldehyde; 2-methyl-3-(4-methylphenyl)propanal; 3,5,6-trimethyl-3-cyclohexene-1-carbaldehyde, 2,4,6-trimethyl-3-cyclohexene-1-carbaldehyde, and mixtures thereof; 4-ethylbenzaldehyde; 6-methoxy-2,6-dimethylheptanal; (E)-non-2-enal; and combinations thereof.

Claims16

Dependent claims

A method,

wherein the method conveys, enhances, improves or modifies an intensity and/or sensitivity of the perception of a floral muguet odor in a subject,
wherein the method comprises contacting the subject with at least one positive allosteric modulator selected from the group consisting of:
octanal;
(E)-dec-2-enal, 2-phenylpropanal;
(E)-but-2-enal;
3-methylbenzaldehyde;
3-(1,3-benzodioxol-5-yl)-2-methylpropanal;
(±)-3-(4-methyl-3-penten-1-yl)-3-cyclohexene-1-carbaldehyde, (±)-4-(4-methyl-3-penten-1-yl)-3-cyclohexene-1-carbaldehyde, and mixtures thereof;
heptanal, 4-Propan-2-ylbenzaldehyde;
(3R)-3,7-dimethyloct-6-enal;
(+)-(3S)-3-[(1R)-4-methyl-3-cyclohexen-1-yl]butanal, (+)-(3R)-3-[(1R)-4-methyl-3-cyclohexen-1-yl]butanal, and mixtures thereof;
hexanal;
2,6-dimethylhept-5-enal;
benzaldehyde;
2-methyl-3-(4-methylphenyl)propanal;
3,5,6-trimethyl-3-cyclohexene-1-carbaldehyde, 2,4,6-trimethyl-3-cyclohexene-1-carbaldehyde, and mixtures thereof;
4-ethylbenzaldehyde;
6-methoxy-2,6-dimethylheptanal;
(E)-non-2-enal;
and combinations thereof,
wherein the subject is contacted with the at least one positive allosteric modulator in an amount sufficient to convey, enhance, improve or modify the intensity and/or sensitivity of the perception of the floral muguet odor in the subject.

18 more elements

Dependencies are inferred from the claim text.