Systems and methods for the preparation of vaccines utilizing predictably inactivated pathogens

A method for producing an immunogenic composition comprising:

• (a) neutering an intact pathogenic source, wherein neutering the pathogenic source involves:
• destroying the genetic material of the pathogenic source by varying a dosage and/or a wavelength of UV-C radiation such that the pathogenic source is unable to reproduce or cause infection while leaving intact at least some or all of its membrane or structural proteins as antigens;
• and
• (b) aliquoting the neutered pathogenic source into containers,
• wherein the pathogenic source is neutered in a disinfectant unit comprising:
• a housing that is opaque to UV-C radiation/light;
• and
• a chamber enclosed within the housing, wherein the chamber comprises:
• (i) a chamber wall that is transparent to UV-C light;
• (ii) a chamber inlet;
• (iii) a chamber outlet;
• (iv) a centralized inner bore having an interior chamber surface facing the inner bore;
• (v) one or more UV-C light source positioned adjacent the interior surface;
• and
• (vi) a helical air flow diverter centralized within the inner bore proximal the one or more UV-C light sources, wherein the helical air flow diverter comprises one or more rungs, wherein the helical airflow diverter creates a centrifugal force and a helical path for the airflow pathway as the airflow pathway proceeds from the housing inlet to the housing outlet, and
• wherein varying the dosage and wavelength of the UV-C radiation involves:
• (A) controlling one or more of the following parameters:
• (i) intensity of UV-C emitted by the one or more UV-C light sources;
• (ii) number, type and position of the one or more UV-C light sources;
• and
• (iii) number of disinfectant units and/or number of chambers per disinfectant unit;
• and/or
• (B) controlling the exposure time of the pathogenic source to the UV-C by adjusting or varying one or more of the following parameters:
• (i) height of the chambers per disinfectant unit to thereby increase the height of the helical air flow diverter,
• (ii) number of helical rungs,
• (iii) a surface on the chamber wall with reflecting and/or irregular or crenulated walls to increase light ray reflections;
• (iv) speed of the air flow through the device,
• (v) a diameter of the helical rungs to control the proximity of the UV-C light source to the pathogens,
• (vi) air flow velocity through the disinfectant unit(s);
• and
• (vii) length of an air stream pathway through the disinfectant unit.