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US 11,951,151 B2Granted
Compositions comprising antimicrobial peptides
AssigneeUniversity of Pittsburgh—Of the Commonwealth System of Higher Education
InventorsKenneth Urish, Jonathan Brendan Mandell
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Abstract
A method of treating or preventing a microbial infection in a patient is provided, along with a wound irrigation system and a composition in the form of an irrigation liquid for reducing microbial load or preventing microbial infection in a wound.
Claims19
A pharmaceutical composition for treating a biofilm comprising:
- a. a cationic antimicrobial peptide or pharmaceutically acceptable salt thereof, wherein the cationic antimicrobial peptide is SEQ ID NO:
- 10;
- and
- b. a pharmaceutically acceptable aqueous carrier;
- wherein the pharmaceutical composition is in the form of a liquid;
- wherein the cationic antimicrobial peptide is present at a concentration of about 10 mg/mL;
- and wherein the pharmaceutical composition is formulated for irrigating an open wound, an implant, a medical device, a prosthetic, or any part thereof.
4 more elements
Dependencies are inferred from the claim text.