A pharmaceutical composition comprising a plant extract as an active ingredient for prevention or treatment of cancer, the plant extract being prepared by a process comprising:
- i) a first step of adding distilled water to Anemone raddeana and performing grinding to prepare a plant medium;
- ii) a second step of adding an organic solvent to flowers of Lonicera japonica, to prepare an extract thereof;
- iii) a third step of combining the plant medium in the first step with the extract in the second step and fermenting the combination at 37° C. while stirring;
- iv) a fourth step of adding an organic solvent to the fermented product obtained in the third step to form fractions;
- v) a fifth step of subjecting the fractions of the fourth step to column chromatography to obtain eluates;
- and vi) a sixth step of adding an organic solvent to the eluates of the fifth step to obtain fractions and drying the fractions to obtain the plant extract.