Therapeutic apoptotic cells for cancer therapy
AssigneeEnlivex Therapeutics RDO Ltd
InventorsShai Novik, Dror Mevorach
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Abstract
Methods of use of early apoptotic cell populations and compositions thereof disclosed herein, including methods of treating a cancer or a tumor, extending survival times of a subject suffering from a cancer or a tumor, and reducing the size or reducing the growth rate of a cancer or a tumor, wherein subjects are administered apoptotic cells or compositions thereof. Cancers may include solid tumors or diffuse cancers, for example leukemia. In certain instances compositions may include additional chemotherapeutic agent. Further, inactivated early apoptotic cell populations are disclosed and methods of making the same.
Claims5
A method of treating or inhibiting tumor growth, delaying tumor progression, reducing tumor load, or reducing incidence of a tumor in a subject, or any combination thereof, the method consisting of administering a composition comprising an early apoptotic mononuclear enriched cell population to said subject, wherein said tumor is a lymphoma, and wherein said method treats or inhibits lymphoma growth, delays lymphoma progression, reduces lymphoma load, reduces incidence of said lymphoma in said subject, or reduces the rate of metastasis of the lymphoma, or any combination thereof, compared with a lymphoma in a subject not administered the early apoptotic cell population.
Dependencies are inferred from the claim text.