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US 11,951,125 B2Granted
Drug and production method therefor
AssigneeOsaka University
InventorsHikaru Kobayashi, Yuki Kobayashi, Ryoichi Imamura, Norio Nonomura
Life of this patent
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Abstract
One drug (solid preparation) 100 of the present invention is a drug for a disease of kidney that contains a silicon fine particle, an aggregate of the silicon fine particles, or a crystal grain of silicon having a hydrogen-generating ability. Hydrogen generated from the silicon fine particle in the drug can contribute to the prevention and/or treatment of the kidney disease.
Claims14
A drug for a disease of a kidney, comprising one or more of (a), (b) or (c):
- (a) an aggregate of silicon fine particles, the aggregate having a size of more than 0.1 μm;
- (b) a crystal grain of silicon, the crystal grain having a particle size of about 1 μm to about 2 μm, and
- (c) one or more hydrogen generating material selected from the group of:
- porous silicon fine particles having a size of more than 100 nm,
- polycrystalline silicon fine particles having a size of more than 100 nm,
- unfree silicon fine particles having a size of more than 100 nm,
- hardly crushed silicon fine particles having a size of more than 100 nm,
- silicon fine particles having a size of more than 100 nm and granulated with an undecomposed binding agent, and
- a porous crystal grain of silicon, the porous crystal grain having a size of more than 100 nm,
- wherein hydrogen is generated by bringing a water-containing liquid in an intestine into contact with the aggregate of silicon fine particles, the crystal grain of silicon or the one or more hydrogen generating material.
7 more elements
Dependencies are inferred from the claim text.