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US 11,951,108 B2Granted
Combination therapy for treating cancer
AssigneeEpizyme, Inc.
InventorMaria Alejandra Raimondi
Life of this patent
Estimating the term…
Abstract
The disclosure relates to a method for treatment of cancer comprising administering to a subject in need thereof a first agent in a therapeutically effective amount and a second agent in a therapeutically effective amount. Preferably, the first agent comprises an EZH2 inhibitor, e.g., tazemetostat or a pharmaceutically acceptable salt thereof. In certain embodiments, the methods of the disclosure are used to treat breast cancer, ovarian cancer, or both.
Claims20
A method for treating ovarian cancer or breast cancer comprising administering to a subject in need thereof
- (a) a therapeutically effective amount of Compound A:
- or a pharmaceutically acceptable salt thereof, and
- (b) a therapeutically effective amount of a PARP inhibitor selected from iniparib and olaparib.
Dependencies are inferred from the claim text.