Method of treating cancer using selective estrogen receptor modulators
AssigneeDuke University
InventorsSuzanne E. Wardell, Erik R. Nelson, Donald P. McDonnell
Life of this patent
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Abstract
Disclosed herein are methods of treating subjects suffering from estrogen receptor positive cancer of the brain by administering a selective estrogen receptor degrader (SERM). Also disclosed are methods of treating a cancer that is resistant to an estrogen receptor modulator by administering a SERM.
Claims11
A method of treating ovarian cancer in a subject, the method comprising administering a compound of (R)-6-{2-{ethyl[4-(2-ethylaminoethyl)benzyl]amino}-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol, wherein the ovarian cancer is estrogen receptor positive, and is resistant to an estrogen receptor modulator.
Dependencies are inferred from the claim text.