Back to results
US 11,951,038 B2Granted
Lacrimal implants and related methods
AssigneeMati Therapeutics Inc.
InventorsAlan R. Rapacki, Valery Rubinchik, John B. Holds, Sylvie Sim, Danny Shen
Life of this patent
Estimating the term…
Abstract
Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.
Claims19
A kit for implanting a lacrimal implant into a lacrimal canaliculus, comprising:
- an insertion tool;
- and,
- a lacrimal implant comprising an implant body, comprising a first and second portions, the implant body non-linearly extending from a proximal end portion positionable within a vertical section of the lacrimal canaliculus to a distal end portion positionable within a horizontal section of the lacrimal canaliculus and having an intermediate portion therebetween, the proximal end of the first portion defining a longitudinal proximal axis and the distal end of the second portion defining a longitudinal distal axis, the first portion including a cavity;
- a therapeutic agent disposed in the cavity;
- the intermediate portion partially extending in a first direction toward the proximal end portion, partially extending in a second direction toward the distal end portion, and partially extending in a third direction along the longitudinal distal axis, configured to bias against a portion of a lacrimal canaliculus ampulla wherein the third direction is perpendicular to the first direction of the intermediate portion, such that, when implanted in the lacrimal canaliculus, the implant body directionally biases laterally against at least a portion of the lacrimal canaliculus located at or more distal to a canalicular curvature.
2 more elements
A kit for insertion of a lacrimal implant into a lacrimal canaliculus, comprising:
- an insertion tool;
- and,
- a lacrimal implant comprising an implant body, including first and second portions, the implant body extending from a proximal end of the first portion to a distal end of the second portion, the first portion including a cavity;
- a therapeutic agent disposed in the cavity;
- the proximal end of the first portion defining a longitudinal proximal axis and the distal end of the second portion defining a longitudinal distal axis and wherein the second portion includes an element extending or expanding laterally into a lacrimal canaliculus ampulla when the implant body is implanted;
- the implant body configured such that, when implanted in the lacrimal canaliculus, an angled intersection exists between the proximal axis and the distal axis for biasing at least a portion of the implant body against at least a portion of the lacrimal canaliculus located at or more distal to a canalicular curvature;
- and
- wherein the second portion of the implant body includes a longitudinal length having a magnitude less than four times a longitudinal length of the first portion of the implant body.
5 more elements
A kit for insertion of a lacrimal implant into a lacrimal canaliculus, comprising:
- an insertion tool;
- and,
- a lacrimal implant comprising an implant body, including first and second portions, the implant body extending from a proximal end of the first portion to a distal end of the second portion, the first portion including a cavity;
- a therapeutic agent disposed in the cavity;
- the proximal end of the first portion defining a longitudinal proximal axis and the distal end of the second portion defining a longitudinal distal axis and wherein the second portion includes an element extending or expanding laterally into a lacrimal canaliculus ampulla when the implant body is implanted;
- and,
- the implant body configured such that, when implanted in the lacrimal canaliculus, an angled intersection exists between the proximal axis and the distal axis for biasing at least a portion of the implant body against at least a portion of the lacrimal canaliculus located at or more distal to a canalicular curvature.
4 more elements
Dependencies are inferred from the claim text.