Ocular delivery systems and methods
AssigneeSight Sciences, Inc.
InventorsDavid Y. Badawi, Daniel O'Keeffe, Paul Badawi
Life of this patent
Estimating the term…
Abstract
Described here are systems and methods for accessing Schlemm's canal and for delivering an ocular device or fluid composition therein. The ocular devices may maintain the patency of Schlemm's canal without substantially interfering with transmural fluid flow across the canal. The fluid composition may be a viscoelastic fluid that is delivered into the canal to facilitate drainage of aqueous humor by disrupting the canal and surrounding trabeculocanalicular tissues. Tools for disrupting these tissues and minimally invasive methods for treating medical conditions associated with elevated intraocular pressure, including glaucoma, are also described.
Claims35
A device for delivering fluids to an eye comprising:
- a cannula;
- a handle comprising a housing having an interior portion and a fluid reservoir moveable within the interior portion of the housing, and a loading component extending from the fluid reservoir and passing through the housing, wherein the cannula is coupled to a distal end of the housing;
- and
- a flexible conduit slidably disposed within, and advanceable distally from, the cannula, the flexible conduit configured to be advanced around an arc of Schlemm's canal and comprising a lumen in fluid communication with the fluid reservoir,
- wherein the housing further comprises a slide configured to deliver fluid through the conduit to Schlemm's canal.
A device for delivering fluids to an eye comprising:
- a cannula;
- a handle comprising a housing having an interior portion and a fluid reservoir moveable within the interior portion of the housing, and a loading component extending from the fluid reservoir and passing through the housing;
- and
- a flexible conduit slidably disposed within, and advanceable distally from, the cannula, the flexible conduit configured to be advanced around an arc of Schlemm's canal and comprising a lumen in fluid communication with the fluid reservoir,
- wherein the housing further comprises a slide fixedly coupled to an elongate member positioned within the handle, wherein the elongate member comprises a lumen therethrough configured to deliver fluid to the flexible conduit.
A device for delivering fluid to an eye comprising:
- a cannula;
- a handle coupled to the cannula, wherein the handle comprises a housing including an interior portion, a fluid reservoir moveable within the interior portion of the housing and a loading component extending from the fluid reservoir and passing through the housing;
- and
- a flexible conduit slidably disposed within, and advanceable distally from, the cannula, wherein the flexible conduit comprises a lumen in fluid communication with the reservoir and the conduit is configured to advance along an arc of Schlemm's canal,
- wherein the device is configured to both advance the flexible conduit from the cannula and deliver a fluid therethrough from the fluid reservoir using the handle.
Dependencies are inferred from the claim text.