US 11,951,005 B2Granted

Implant for heart valve

AssigneeCardiovalve Ltd.

InventorsYossi Gross, Gil Hacohen

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Abstract

A heart valve repair system includes a delivery sheath and an implant that includes a frame including a braided structure of intertwining strands and having a surface configured to contact an upstream surface of a native heart valve. First and second gripping members are coupled to the frame, each including atrial and ventricular arms. The implant is disposed in the sheath in a delivery state in which the frame defines a wall fully surrounding a central longitudinal axis of the implant. The distal end of the wall defines a distal opening of the frame. The distal end of the wall is disposed proximally to the second end of the ventricular arm of each of the gripping members. The second end of each ventricular arm moves toward the axis of the implant more than the first end moves toward the axis. Other embodiments are also described.

Claims28

Dependent claims

A heart valve repair system, comprising:

a delivery sheath having a proximal end and a distal end;
and
an implant configured to be coupled to first and second native leaflets of a native heart valve of a patient, the implant comprising:
a frame (1) comprising a braided structure of intertwining strands and (2) having a surface configured to contact an upstream surface of the native heart valve;
and
first and second gripping members coupled to the frame, each of the first and second gripping members including (i) a ventricular arm, the ventricular arm having first and second ends, and (ii) an atrial arm, wherein for each of the gripping members:
(A) the ventricular arm is movable toward a central longitudinal axis of the implant, and
(B) due to the moving of the ventricular arm toward the central longitudinal axis, the second end of the ventricular arm moves toward the central longitudinal axis more than the first end of the ventricular arm moves toward the central longitudinal axis of the implant,
wherein the implant is disposed in the delivery sheath in a delivery state in which:
the frame has a proximal end, closer to the proximal end of the delivery sheath, and a distal end, closer to the distal end of the delivery sheath,
the frame is shaped to define a wall fully surrounding, from a proximal end of the wall to a distal end of the wall, the central longitudinal axis of the implant, the proximal end of the wall defining a proximal opening of the frame, and the distal end of the wall defining a distal opening of the frame, and
the distal end of the wall is disposed proximally to the second end of the ventricular arm of each of the gripping members.

9 more elements

A heart valve repair system, comprising:

a delivery sheath having a proximal end and a distal end;
and
an implant configured to be coupled to first and second native leaflets of a native heart valve of a patient, the implant comprising:
a frame having a surface configured to contact an upstream surface of the native heart valve;
and
first and second gripping members coupled to the frame, each of the first and second gripping members including (i) a ventricular arm, the ventricular arm having first and second ends, and (ii) an atrial arm, wherein for each of the gripping members:
(A) the ventricular arm is movable toward a central longitudinal axis of the implant, and
(B) due to the moving of the ventricular arm toward the central longitudinal axis, the second end of the ventricular arm moves toward the central longitudinal axis more than the first end of the ventricular arm moves toward the central longitudinal axis of the implant,
wherein the implant is disposed in the delivery sheath in a delivery state in which:
the frame has a proximal end, closer to the proximal end of the delivery sheath, and a distal end, closer to the distal end of the delivery sheath,
the frame is shaped to define a wall fully surrounding, from a proximal end of the wall to a distal end of the wall, the central longitudinal axis of the implant, the proximal end of the wall defining a proximal opening of the frame, and the distal end of the wall defining a distal opening of the frame, and
the distal end of the wall is disposed proximally to the second end of the ventricular arm of each of the gripping members, and
wherein the implant is configured to assume an implanted state in which, following the moving of the ventricular arm of each of the gripping members toward the central longitudinal axis of the implant, the first and second gripping members form the first and second native leaflets into a double orifice, each orifice configured to function as a respective check-valve.

10 more elements

A heart valve repair system, comprising:

a delivery sheath having a proximal end and a distal end;
and
an implant configured to be coupled to first and second native leaflets of a native heart valve of a patient, the implant comprising:
a frame having a surface configured to contact an upstream surface of the native heart valve;
and
first and second gripping members coupled to the frame, each of the first and second gripping members including (i) a ventricular arm, the ventricular arm having first and second ends, and (ii) an atrial arm, wherein for each of the gripping members:
(A) the ventricular arm is movable toward a central longitudinal axis of the implant, and
(B) due to the moving of the ventricular arm toward the central longitudinal axis, the second end of the ventricular arm moves toward the central longitudinal axis more than the first end of the ventricular arm moves toward the central longitudinal axis of the implant,
wherein the implant is disposed in the delivery sheath in a delivery state in which:
the frame has a proximal end, closer to the proximal end of the delivery sheath, and a distal end, closer to the distal end of the delivery sheath,
the frame is shaped to define a wall fully surrounding, from a proximal end of the wall to a distal end of the wall, the central longitudinal axis of the implant, the proximal end of the wall defining a proximal opening of the frame, and the distal end of the wall defining a distal opening of the frame, and
the distal end of the wall is disposed proximally to the second end of the ventricular arm of each of the gripping members, and
wherein the heart valve repair system further comprises an elongate control member that is:
movable within the delivery sheath,
reversibly couplable to the implant, and
extracorporeally controllable to facilitate the moving of each of the ventricular arms,
wherein in the delivery state, the wall of the frame surrounds a space through which the elongate control member is movable.

14 more elements

A heart valve repair system, comprising:

a delivery sheath having a proximal end and a distal end;
and
an implant configured to be coupled to first and second native leaflets of a native heart valve of a patient, the implant comprising:
a frame having a surface configured to contact an upstream surface of the native heart valve;
and
first and second gripping members coupled to the frame, each of the first and second gripping members including (i) a ventricular arm, the ventricular arm having first and second ends, and (ii) an atrial arm, wherein for each of the gripping members:
(A) the ventricular arm is movable toward a central longitudinal axis of the implant, and
(B) due to the moving of the ventricular arm toward the central longitudinal axis, the second end of the ventricular arm moves toward the central longitudinal axis more than the first end of the ventricular arm moves toward the central longitudinal axis of the implant,
wherein the implant is disposed in the delivery sheath in a delivery state in which:
the frame has a proximal end, closer to the proximal end of the delivery sheath, and a distal end, closer to the distal end of the delivery sheath,
the frame is shaped to define a wall fully surrounding, from a proximal end of the wall to a distal end of the wall, the central longitudinal axis of the implant, the proximal end of the wall defining a proximal opening of the frame, and the distal end of the wall defining a distal opening of the frame, and
the distal end of the wall is disposed proximally to the second end of the ventricular arm of each of the gripping members, and
wherein the implant further comprises first and second gripping member mounts to which the first and second gripping members are mounted, respectively.

10 more elements

Dependencies are inferred from the claim text.

Facts

Application: 18/218,419Filed 5 Jul 2023 · continuation
Priority: 5 Aug 2011
Published: US 2023/0058653 A12 Nov 2023
Granted: 9 Apr 2024
Term ends: Not estimatedThe source records don’t support an estimate.

Classification31 codes

A61F 2/2418
With soft flexible valve members, e.g. tissue valves shaped like natural valves: scaffolds therefor, e.g. support stents
A61B 17/122
For ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord: clamps or clips, e.g. for the umbilical cord
A61F 2/2409
Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the…:…
A61F 2/2436
Devices for manipulating or deploying heart valves during implantation: deployment by retracting a sheath

Family

Application61/515,372Us provisional application · filed 5 Aug 2011
Application61/525,281Us provisional application · filed 19 Aug 2011
Application61/537,276Us provisional application · filed 21 Sep 2011
Application61/555,160Us provisional application · filed 3 Nov 2011
Application61/588,892Us provisional application · filed 20 Jan 2012
Application13/412,814Parent of this continuation-in-part · filed 6 Mar 2012
PCT/IL2012/000293Parent of this continuation · filed 5 Aug 2012
US 8,852,272 B2Parent of this continuation-in-part · filed 7 Oct 2014
Application15/197,069Parent of this continuation · filed 29 Jun 2016
US 9,387,078 B2Parent of this continuation · filed 12 Jul 2016
Application16/284,331Parent of this continuation · filed 25 Feb 2019
US 10,226,341 B2Parent of this continuation · filed 12 Mar 2019
Application16/888,210Parent of this continuation · filed 29 May 2020
US 10,702,385 B2Parent of this continuation · filed 7 Jul 2020
Application17/982,897Parent of this continuation · filed 8 Nov 2022
US 11,517,436 B2Parent of this continuation · filed 6 Dec 2022
US 2023/0346550 A1Pre-grant publication · published 2 Nov 2023
US 11,864,995 B2Parent of this continuation
Application14/237,258Parent of this continuation
Application14/237,258Parent of this continuation-in-part
US 2013/0035759 A1Published application
US 2014/0257475 A1Published application
US 2016/0310274 A1Published application
US 2019/0183644 A1Published application
US 2020/0330227 A1Published application
US 2023/0058653 A1Published application
US 11,951,005 B2This patent

From the US filing history. Foreign family members aren’t listed.