Micro biosensor and method for reducing measurement interference using the same

A micro biosensor for implantation under a skin to perform a measurement of a physiological parameter of a target analyte in a biofluid and reduce an interference of at least one interferant in the biofluid on the measurement, the micro biosensor comprising:

• a substrate having a surface;
• a first working electrode including a first sensing section configured on the surface, wherein the first sensing section includes a first conductive material;
• at least one second working electrode configured on the surface and including a second sensing section configured adjacent to the first sensing section of the first working electrode and surrounds three sides of the first sensing section to form a U-shape structure, wherein the second sensing section includes a second conductive material different from the first conductive material;
• and
• a chemical reagent covered on at least a portion of the first conductive material for reacting with the target analyte in the biofluid to produce a resultant, wherein:
• the first working electrode is driven by a first working voltage to cause the first conductive material, having a first sensitivity to the resultant and producing a measurement range, to react with the resultant for outputting a physiological signal corresponding to the physiological parameter of the target analyte;
• and
• the second working electrode is driven by a second working voltage to allow the second conductive material, having a second sensitivity to the resultant smaller than the first sensitivity and producing an interference eliminating range, wherein the U-shape structure enables the interference eliminating range to at least partially overlap with the measurement range to directly consume the interferant for reducing a generation of an interfering current signal at the first working electrode.