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US 11,950,795 B1Granted
Devices, systems and methods to image blood clots
AssigneeIschemicure Ltd.
InventorPaul A. Spence
Life of this patent
Estimating the term…
Abstract
Systems, devices and methods for removing a blood clot (10) from a blood vessel (12). Various uses of suction pressure and positive pressure, proximal and/or distal to the blood clot (10) assist with clot dislodgement and removal. The pressure(s) may be constant and/or cycled/pulsed to assist with clot dislodgement and/or removal. Various further devices assist with separating the clot (10) from the vessel (12).
Claims30
A method of imaging a blood clot within a blood vessel, the method comprising:
- introducing an elongate body having a radially expandable distal seal beyond the blood clot such that the distal seal is disposed distal to the blood clot;
- under fluoroscopic imaging with the distal seal disposed distal to the blood clot, introducing via the elongate body a fluid imaging agent through a perforation in the elongate body disposed between a proximal end of the distal seal and a distal end of the distal seal (1) to provide a uniform pressurized region within an area defined between a distal end of the blood clot and the distal end of the distal seal and (2) to radially pressurize the distal seal against an interior wall surface of the blood vessel distal to the blood clot;
- and
- imaging the imaging agent within the blood vessel to identify at least a portion of the blood clot within the blood vessel.
1 more element
A method, comprising:
- introducing an elongate body having a radially expandable distal seal distally from a location within the blood vessel proximal to the blood clot, beyond the blood clot such that the distal seal is disposed distal to the blood clot, the distal seal defining an opening at a proximal portion thereof and being a membrane;
- introducing an imaging agent through a lumen and at least one perforation of the elongate body into an area between the blood clot and a distal end of the distal seal to increase a pressure within the area to expand the distal seal to form a fluid pressure seal against an interior wall surface of the blood vessel distal to the blood clot, the at least one perforation being located distal to the proximal end of the distal seal and proximal to a distal end of the distal seal;
- and
- imaging at least a portion of the blood clot within the blood vessel based on the imaging agent.
1 more element
A method of imaging the distal end of a blood clot that is lodged in and obstructing a blood vessel, and of removing the blood clot intact from the blood vessel, the method comprising:
- introducing into the vessel proximal to the blood clot a suction catheter defining a lumen therethrough;
- introducing through the lumen of the suction catheter an elongate member defining a lumen therethrough and defining one or more perforations at a distal end portion thereof, the elongate body having an inflatable membrane seal mounted to a distal portion thereof, with at least one of the one or more perforations disposed distal to a proximal end of the inflatable membrane seal;
- advancing the elongate member until the distal portion thereof is disposed distal to the blood clot;
- causing the inflatable membrane seal to expand radially against a portion of an interior wall surface of the blood vessel distal to the blood clot by introducing through the lumen and the at least one perforation a liquid dye;
- pressurizing an area of the blood vessel distal to the blood clot and proximal to the portion of the interior wall surface by further introducing through the lumen and the at least one perforation more of the liquid dye;
- imaging the liquid dye within the blood vessel distal to the blood clot to identify at least the distal end of the blood clot;
- applying suction pressure through the lumen of the catheter to the blood vessel proximal to the blood clot;
- dislodging the blood clot from the blood vessel;
- moving the blood clot intact toward the suction catheter;
- capturing the proximal end of the blood clot with the suction catheter;
- and
- withdrawing the suction catheter from the vessel to remove the blood clot from the vessel intact and unfractured.
9 more elements
Dependencies are inferred from the claim text.