Acquisition of interferometric recordings of brain and neuron activity by coherent microwave probe with therapeutic activation, inactivation, or ablation of molecular, neuronal or brain targets
AssigneeEmad Eskandar
InventorsEmad N. Eskandar, James Joseph Cohen
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Abstract
Low power MASER (Microwave Amplification by Stimulated Emission of Radiation) radiation is used to non-invasively record molecular activity in a biological object such as a brain. Low power MASER radiation is also used to neuromodulate molecular targets via Rabi coupling, resulting for example in conformational and function change in specific molecular targets such as ligand-gated ion channels, voltage-gated ion channels, G-proteins, or dopamine receptors. The method can be used to change the energy state of targeted molecules via energization or enervation, or to ablate targeted molecules.
Claims12
A method of transferring energy via MASER radiation to one or more molecular targets in a biological object, the method comprising the steps of:
- emitting a probe beam of coherent MASER radiation by an emitter array and passing the emitted beam through a collimator, wherein the probe beam is modulated to change its instantaneous frequency;
- selecting a characteristic frequency to Rabi couple one of more molecular targets;
- modulating the probe beam so that its instantaneous frequency matches the characteristic frequency;
- passing the modulated probe beam through the object in which the one or more molecular targets are expected to reside;
- shifting the phase of the modulated probe beam in order to Rabi couple the probe beam to said one or more molecular targets in the biological object and transfer energy to the respective Rabi coupled molecular targets.
Dependencies are inferred from the claim text.