Self-assembling insect ferritin nanoparticles

A recombinant insect ferritin nanoparticle, comprising:

• twelve recombinant ferritin heavy chains and twelve recombinant ferritin light chains self-assembled into a globular ferritin nanoparticle;
• wherein
• (A)
• the recombinant insect ferritin heavy chains consist of 172 to 174 amino acids from the C-terminus of an insect ferritin heavy chain;
• the recombinant insect ferritin light chains consist of 182 to 184 amino acids or 177 amino acids from the C-terminus of an insect ferritin light chain;
• and
• each of the ferritin heavy and light chains is fused N terminally to a viral protein;
• and
• (B)
• the recombinant ferritin heavy chains consist of an amino acid sequence at least 90% identical to SEQ ID NO:
• 2;
• and the recombinant ferritin light chains consist of an amino acid sequence at least 90% identical to SEQ ID NO:
• 6;
• or
• the recombinant ferritin heavy chains each consist of an amino acid sequence at least 90% identical to SEQ ID NO:
• 4;
• and the recombinant ferritin light chains each consist of an amino acid sequence at least 90% identical to SEQ ID NO:
• 8.