Biphenyl derivative compound and use thereof
AssigneeEwha University-Industry Collaboration Foundation
InventorsKong Joo Lee, Hee-Yoon Lee, Je Jin Lee, Hwang Suk Kim, Ji-Wan Seo, Hongsoo Lee, Ji Soo Shin, Bo-kyung Kim
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Abstract
The present disclosure provides a novel biphenyl derivative compound or a pharmaceutically acceptable salt thereof. The biphenyl derivative compound or pharmaceutically acceptable salt thereof according to the present disclosure is a compound that increases Nm23-H1/NDPK activity and can inhibit cancer metastasis and growth. Thus, it exhibits excellent effects not only on the prevention, alleviation and treatment of cancer, but also on the suppression of cancer metastasis.
Claims13
A biphenyl derivative compound of the following Formula 1 or a pharmaceutically acceptable salt thereof:
- wherein
- L is —(CH2—CH2)—, and
- each of R1, R2, R3 and R4 is independently hydroxy or methoxy.
Dependencies are inferred from the claim text.