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US 11,939,294 B1Granted
1-(2-(substituted phenyl)-2-oxoethyl)-3,5-dimethylpyridin-1-ium bromides as antitubercular agents
AssigneeKing Faisal University
InventorsKatharigatta N. Venugopala, Mahmoud Kandeel, Melendran Pillay, Osama I. Alwassil, Mohamed A. Morsy, Rashmi Venugopala, Sandeep Chandrashekharappa, Bandar E. Aldhubiab
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Abstract
Compounds for treating tuberculosis and, particularly, to anti-tubercular compounds that are 1-(2-(substitutedphenyl)-2-oxoethyl)-3,5-dimethylpyridin-1-ium bromides and their use as anti-tubercular agents.
Claims8
A method of treating tuberculosis in a patient, comprising administering to a patient in need thereof a therapeutically effective amount of a compound having the formula I:
- or a pharmaceutically acceptable salt, ester, stereoisomer, or solvate thereof, wherein:
- one or more R1 groups is attached to the phenyl ring, wherein each R1 is independently selected from the group consisting of trihalomethyl, methoxy, NO2, and a halogen.
Dependencies are inferred from the claim text.