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US 11,933,791 B2Granted
GDF15 in glaucoma and methods of use thereof
AssigneeWashington University
InventorsRajendra S. Apte, Jun Yoshino
Life of this patent
Estimating the term…
Abstract
Provided herein are methods for determining the severity of glaucoma using expression levels of GDF15. Determining the severity of glaucoma can aid in making treatment decisions.
Claims19
A method of determining glaucoma severity in a human subject, the method comprising:
- a) providing an amount of GDF15 protein in a biological sample selected from the group consisting of tears, aqueous humor, retinal tissue, vitreous, serum, and plasma obtained from the human subject;
- b) comparing the amount of GDF15 protein in the biological sample to a reference value, wherein the amount of GDF15 protein above the reference value indicates glaucoma severity;
- and
- c) administering a therapeutically effective amount of prescription eye drops, or administering laser surgery, or incisional surgery to the subject based on the determined glaucoma severity level.
1 more element
Dependencies are inferred from the claim text.