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US 11,933,700 B2Granted
Analytical system comprising sample management module and method thereof
OwnerXiyuan Suninventor
Life of this patent
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Abstract
The present invention provides an analytical system comprising a sample management module. A pressure delivery assembly is configured to compress and deform a mixing chamber containing a sample preparation, and simultaneously open a plug of the mixing chamber to release the sample preparation. The system can be manufactured as a sample box combinable to a detector box, and is particularly convenient for patients to use at home, for example, screening colorectal cancer with their fecal sample.
Claims20
An analytical system comprising a sample collection module, a sample management module, and a sample analysis module;
- wherein the sample management module comprises:
- a mixing chamber for receiving an amount of sample from the sample collection module and mixing the received sample with a liquid to formulate a sample preparation, wherein the mixing chamber includes an outlet opening for releasing the sample preparation from the mixing chamber;
- a sample tray below the mixing chamber, the sample tray having a raised and enclosed rim to define a receptacle area for receiving an amount of the sample preparation released from the mixing chamber, wherein an island is protruded out from the receptacle area, and the island engages with the outlet opening of the mixing chamber and seals the outlet opening to prevent releasing of the sample preparation through it;
- and
- a pressure delivery assembly comprising a lower member below the sample tray and an upper member above the sample tray for contacting against the mixing chamber, wherein the lower member is contactable to the upper member, and a force from the lower member can be exerted up against the upper member which transmits the force along against the mixing chamber so as to squeeze and deform the mixing chamber, reduce a volume thereof, and in the meanwhile, disengage the outlet opening from the island to unseal the outlet opening, and release an amount of the sample preparation from the mixing chamber into the receptacle area;
- wherein the pressure delivery assembly (80) further comprises an alignment channel (83) to align the lower member's (81) movement and the upper member's (82) movement before the two members (81) and (82) meet and contact each other;
- and
- wherein said sample preparation released into the receptacle area is delivered to the sample analysis module.
5 more elements
Dependencies are inferred from the claim text.