Back to results
US 11,925,741 B2Granted
Biological component collection device with internal pressure sensor and method
AssigneeTerumo Kabushiki Kaisha
InventorMasatsugu Igarashi
Life of this patent
Estimating the term…
Abstract
In a blood transfusion system (a blood transfusion kit, a blood transfusion kit for emergency blood transfusion, or a method of using a blood transfusion kit), a flow path through which blood flows is formed using a tube having a channel therein. The flow path includes: a first path that connects an upstream path and a downstream path and has a leukocyte removal filter removing leukocytes at an intermediate position of the channel and a second path that connects the upstream path and the downstream path and bypasses the leukocyte removal filter.
Claims18
A biological component collection device configured to be attachable to a separation device equipped with a first load detector, the biological component collection device comprising:
- a cassette body comprising:
- a flow path through which liquid flows, the flow path including a first branch and a second branch that is spaced apart from the first branch in a first direction on a surface of the cassette body;
- a first port at a first end of the cassette body, wherein the liquid enters or exits the cassette body through the first port;
- a first coupling member adjacent to the first port at the first end of the cassette body and that connects the first port, the first branch, and the second branch;
- a second port at a second end of the cassette body opposite the first end, wherein the liquid enters or exits the cassette body through the second port;
- a second coupling member adjacent to the second port at the second end of the cassette body and that connects the second port, the first branch, and the second branch, wherein the first branch and the second branch are spaced apart from one another along a length of the surface of the cassette body that corresponds to a distance between the first coupling member and the second coupling member;
- a first soft portion in the first branch of the flow path, and which is pressable by the first load detector of the separation device;
- and
- a second soft portion in the second branch of the flow path, wherein the second soft portion is more easily deformable than the first soft portion, and is pressable by a second load detector.
6 more elements
A biological component collection system comprising:
- a separation device having a first load detector and a second load detector, and for separating a biological component from a liquid containing at least one biological component;
- a biological component collection device configured to be attachable to the separation device, wherein a circuit internal pressure is calculated from said first load detector and from said second load detector;
- wherein the biological component collection device comprises a cassette body, the cassette body comprising:
- a flow path through which the liquid flows, the flow path including a first branch and a second branch that is spaced apart from the first branch in a first direction on a surface of the cassette body;
- a first port at a first end of the cassette body, wherein the liquid enters or exits the cassette body through the first port;
- a first coupling member adjacent to the first port at the first end of the cassette body and that connects the first port, the first branch, and the second branch;
- a second port at a second end of the cassette body opposite the first end, wherein the liquid enters or exits the cassette body through the second port;
- a second coupling member adjacent to the second port at the second end of the cassette body and that connects the second port, the first branch, and the second branch, wherein the first branch and the second branch are spaced apart from one another along a length of the surface of the cassette body that corresponds to a distance between the first coupling member and the second coupling member;
- a first soft portion in the first branch of the flow path, and which is pressed by the first load detector when the separation device is in operation;
- and
- a second soft portion in the second branch of the flow path, and which is pressed by the second load detector;
- wherein the second soft portion is more easily deformable than the first soft portion, and
- wherein the circuit internal pressure is calculated using data acquired by the first load detector and reference data acquired by the second load detector.
10 more elements
A circuit internal pressure acquisition method for measuring a circuit internal pressure of a biological component collection device attached to a separation device having a first load detector and a second load detector, the separation device being adapted to separate a biological component from a liquid containing at least one biological component;
- wherein the biological component collection device comprises:
- a cassette body comprising:
- a flow path through which liquid flows, the flow path including a first branch and a second branch that is spaced apart from the first branch in a first direction on a surface of the cassette body;
- a first port at a first end of the cassette body, wherein the liquid enters or exits the cassette body through the first port;
- a first coupling member adjacent to the first port at the first end of the cassette body and that connects the first port, the first branch, and the second branch;
- a second port at a second end of the cassette body opposite the first end, wherein the liquid enters or exits the cassette body through the second port;
- a second coupling member adjacent to the second port at the second end of the cassette body and that connects the second port, the first branch, and the second branch, wherein the first branch and the second branch are spaced apart from one another along a length of the surface of the cassette body that corresponds to a distance between the first coupling member and the second coupling member;
- a first soft portion in the first branch of the flow path, and which is pressable by the first load detector of the separation device;
- and
- a second soft portion in the second branch of the flow path, wherein the second soft portion is more easily deformable than the first soft portion, and is pressable by the second load detector,
- wherein the circuit internal pressure acquisition method comprises:
- a data acquisition step of acquiring data for correcting reference data to be used when calculating the circuit internal pressure, by detecting with the second load detector a load received from the second soft portion in a state in which a pressurized fluid is introduced into the second branch of the flow path;
- a correction step of correcting the reference data, using the data acquired by the second load detector;
- and
- an internal pressure calculation step of calculating the circuit internal pressure of the biological component collection device, using the data acquired by the first load detector and the corrected reference data.
12 more elements
Dependencies are inferred from the claim text.