An extracorporeal system for treating a subject infected with SARS-CoV-2 comprising at least three adsorbent materials, and a computer system, wherein the adsorbent materials comprise an synthetic carbon particle, a mixture of a synthetic carbon particle (SCP) and an anion exchatnre resin, wherein the weight ratio of SCP to anion exchange resin is from about 1:100, and a mixture of an synthetic carbon particle and a cation exchange resin, wherein the weight ratio of SCP to cation exchange resin is from about 1:100.