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US 11,918,718 B2Granted
Molecularly imprinted polymers for removal of trimethylamine N-oxide
AssigneeUniversity of Washington
InventorsBuddy D. Ratner, Runbang Tang
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Abstract
The present disclosure features a composition, including molecularly imprinted crosslinked polymers that have been imprinted with trimethylamine N-oxide. The molecularly imprinted crosslinked polymers have specific binding sites for trimethylamine N-oxide, and a trimethylamine N-oxide absorption capacity of at least 0.5 mg/g.
Claims5
A method of making a crosslinked polymer, comprising:
- polymerizing a monomer comprising a (C0-6alkyl)acrylic acid, di(C1-6alkyl)acrylic acid, or a combination thereof;
- and a crosslinker comprising a (C1-6 alkylene glycol)-di(C1-6alkyl)acrylate, trimethylolpropane trimethacrylate, N,N′-methylenebisacrylamide, or any combination thereof;
- at a monomer:crosslinker ratio of from 1:9 to 14:1, in the presence of trimethylamine N-oxide and a solvent, to provide the crosslinked polymer,
- wherein the crosslinked polymer comprises specific binding sites for trimethylamine N-oxide and a trimethylamine N-oxide absorption capacity of at least 0.5 mg/g.
1 more element
Dependencies are inferred from the claim text.