Techniques for acquisition-stage peak width determination and baseline offset estimation
AssigneeWaters Technologies Ireland Limited
InventorJose L. De Corral
Life of this patent
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Abstract
Techniques and apparatus for an acquisition-stage peak width determination process are described. In one embodiment, for example, an apparatus may include at least one memory, and logic coupled to the at least one memory. The logic may be configured to implement an acquisition-stage peak width determination process operative to access acquisition-stage analytical information comprising at least one sequence of data points, determine a peak data point associated based on the peak data point meeting a plurality of acquisition-stage conditions, and determine the acquisition-stage peak width associated with the peak data point. Other embodiments are described.
Claims30
An apparatus, comprising:
- at least one memory;
- and
- logic coupled to the at least one memory to determine acquisition-stage peak width information, the logic to:
- detect a plurality of acquisition-stage peaks representing peaks in a sequence of data points acquired by a mass analyzer and perform rough peak width estimation per peak,
- generate an estimated peak width per peak, and
- determine a final peak width based on the estimated peak width per peak.
An apparatus, comprising:
- at least one memory;
- and
- logic coupled to the at least one memory, the logic to implement an acquisition-stage peak width determination process operative to:
- access acquisition-stage analytical information comprising at least one sequence of data points,
- determine a peak data point associated based on the peak data point meeting a plurality of acquisition-stage conditions, and
- determine the acquisition-stage peak width associated with the peak data point.
A method to implement an acquisition-stage peak width determination process, the method comprising:
- accessing acquisition-stage analytical information comprising at least one sequence of data points;
- determining a peak data point associated based on the peak data point meeting a plurality of acquisition-stage conditions;
- and
- determining the acquisition-stage peak width associated with the peak data point.
An apparatus, comprising:
- at least one memory;
- and
- logic coupled to the at least one memory, the logic operative to implement a baseline offset estimation process operative to:
- determine a Gaussian curve having an apex intensity peakY that equals a Gaussian intensity plus a peak offset intensity peakOffset,
- determine a sequence of N data points of the Gaussian curve, comprising an apex point and adjacent points with an intensity greater than or equal to half the apex intensity,
- determine a table of a plurality of Gaussian top-part ratio values, wherein each of the plurality of Gaussian top-part ratio values corresponds with a Gaussian offset ratio value,
- determine a Gaussian top-part ratio value based on an average intensity of the sequence of N data points over the apex intensity,
- determine a Gaussian offset ratio value based on the Gaussian top-part ratio value and the table.
Dependencies are inferred from the claim text.